Founder and CEO of Biotechnology company Profluent Ali Madani revealed today that his team has successfully edited DNA in human cells using gene editors entirely designed by artificial intelligence. Furthermore, these newly created molecules will be made available for free under the OpenCRISPR initiative, potentially revolutionizing how researchers approach gene editing.
This innovation stems from Profluent’s use of large language models (LLMs) trained on extensive biological datasets to create millions of diverse CRISPR-like proteins. These proteins, which do not occur naturally, expand the scope of CRISPR technology by introducing novel cas9-like proteins and guide RNAs (gRNAs) that are significantly different from any existing in nature. According to Madani, these AI-designed tools have demonstrated comparable or superior activity and specificity relative to SpCas9, a widely used gene editing effector.
The enhanced capabilities of these AI-generated gene editors were confirmed thr
We współpracy z: https://cryptoslate.com/ai-based-human-gene-editing-breakthrough-opens-path-to-open-source-cures-to-disease-slow-aging/
